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TitleNew Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15
Journal, issue, pagesJ. Virol., Vol. 80, Page 7909-7917, Year 2006
Publish dateApr 28, 2006 (structure data deposition date)
AuthorsXu, X. / Zhai, Y. / Sun, F. / Lou, Z. / Su, D. / Xu, Y. / Zhang, R. / Joachimiak, A. / Zhang, X.C. / Bartlam, M. / Rao, Z.
External linksJ. Virol. / PubMed:16873248
MethodsX-ray diffraction
Resolution2.15 - 2.7 Å
Structure data

PDB-2gth:
crystal structure of the wildtype MHV coronavirus non-structural protein nsp15
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2gti:
mutation of MHV coronavirus non-structural protein nsp15 (F307L)
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • murine hepatitis virus
KeywordsVIRAL PROTEIN / MHV / nsp15 / F307L

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