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Structure paper

TitleCrystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 28480-28487, Year 2006
Publish dateMay 22, 2006 (structure data deposition date)
AuthorsHsiao, Y.-S. / Jogl, G. / Tong, L.
External linksJ. Biol. Chem. / PubMed:16870616
MethodsX-ray diffraction
Resolution1.9 - 2.2 Å
Structure data

PDB-2h3p:
Crystal structure of murine carnitine acetyltransferase in complex with carnitine and acetyl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2h3u:
Crystal structure of murine carnitine acetyltransferase in complex with carnitine and CoA
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2h3w:
Crystal structure of the S554A/M564G mutant of murine carnitine acetyltransferase in complex with hexanoylcarnitine and CoA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-COA:
COENZYME A

ChemComp-152:
CARNITINE

ChemComp-ACO:
ACETYL COENZYME *A

ChemComp-HOH:
WATER

ChemComp-HC5:
(R)-3-CARBOXY-2-(HEXANOYLOXY)-N,N,N-TRIMETHYLPROPAN-1-AMINIUM

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / carnitine acyltransferase

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