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TitleStructural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 103, Page 11503-11508, Year 2006
Publish dateFeb 15, 2005 (structure data deposition date)
AuthorsWang, S.X. / Pandey, K.C. / Somoza, J.R. / Sijwali, P.S. / Kortemme, T. / Brinen, L.S. / Fletterick, R.J. / Rosenthal, P.J. / McKerrow, J.H.
External linksProc. Natl. Acad. Sci. Usa / PubMed:16864794
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-1yvb:
the Plasmodium falciparum Cysteine Protease Falcipain-2
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • gallus gallus (chicken)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / cysteine protease-inhibitor complex / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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