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-Structure paper
Title | Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 49, Page 4455-4458, Year 2006 |
Publish date | Jun 9, 2006 (structure data deposition date) |
Authors | Zhao, H. / Serby, M.D. / Xin, Z. / Szczepankiewicz, B.G. / Liu, M. / Kosogof, C. / Liu, B. / Nelson, L.T. / Johnson, E.F. / Wang, S. ...Zhao, H. / Serby, M.D. / Xin, Z. / Szczepankiewicz, B.G. / Liu, M. / Kosogof, C. / Liu, B. / Nelson, L.T. / Johnson, E.F. / Wang, S. / Pederson, T. / Gum, R.J. / Clampit, J.E. / Haasch, D.L. / Abad-Zapatero, C. / Fry, E.H. / Rondinone, C. / Trevillyan, J.M. / Sham, H.L. / Liu, G. |
External links | J. Med. Chem. / PubMed:16854050 |
Methods | X-ray diffraction |
Resolution | 3 Å |
Structure data | PDB-2h96: |
Chemicals | ChemComp-SO4: ChemComp-893: ChemComp-GOL: |
Source |
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Keywords | TRANSCRIPTION / JNK1 / C-JUN N-TERMINAL KINASE / PROTEIN KINASE JNK1 INHIBITORS / PYRIDINE CARBOXAMIDE INHIBITORS |