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-Structure paper
Title | Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 4834-4838, Year 2006 |
Publish date | Jun 12, 2006 (structure data deposition date) |
![]() | Li, H. / Tatlock, J. / Linton, A. / Gonzalez, J. / Borchardt, A. / Dragovich, P. / Jewell, T. / Prins, T. / Zhou, R. / Blazel, J. ...Li, H. / Tatlock, J. / Linton, A. / Gonzalez, J. / Borchardt, A. / Dragovich, P. / Jewell, T. / Prins, T. / Zhou, R. / Blazel, J. / Parge, H. / Love, R. / Hickey, M. / Doan, C. / Shi, S. / Duggal, R. / Lewis, C. / Fuhrman, S. |
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Methods | X-ray diffraction |
Resolution | 1.58 Å |
Structure data | ![]() PDB-2hai: |
Chemicals | ![]() ChemComp-PFI: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / HCV RNA Polymerase |