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IF

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Structure paper

TitleIK682, a tight binding inhibitor of TACE.
Journal, issue, pagesArch. Biochem. Biophys., Vol. 451, Page 43-50, Year 2006
Publish dateJan 30, 2006 (structure data deposition date)
AuthorsNiu, X. / Umland, S. / Ingram, R. / Beyer, B.M. / Liu, Y.H. / Sun, J. / Lundell, D. / Orth, P.
External linksArch. Biochem. Biophys. / PubMed:16762314
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-2fv5:
Crystal structure of TACE in complex with IK682
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-541:
(2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / TACE ADAM17 ZN-ENDOPEPTIDASE

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