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-Structure paper
Title | Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 4252-4256, Year 2006 |
Publish date | May 13, 2006 (structure data deposition date) |
Authors | Amarasinghe, K.K. / Evdokimov, A.G. / Xu, K. / Clark, C.M. / Maier, M.B. / Srivastava, A. / Colson, A.O. / Gerwe, G.S. / Stake, G.E. / Howard, B.W. ...Amarasinghe, K.K. / Evdokimov, A.G. / Xu, K. / Clark, C.M. / Maier, M.B. / Srivastava, A. / Colson, A.O. / Gerwe, G.S. / Stake, G.E. / Howard, B.W. / Pokross, M.E. / Gray, J.L. / Peters, K.G. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16759857 |
Methods | X-ray diffraction |
Resolution | 1.65 - 2.3 Å |
Structure data | PDB-2h02: PDB-2h03: PDB-2h04: |
Chemicals | ChemComp-2UN: ChemComp-HOH: ChemComp-CL: ChemComp-MG: ChemComp-3UN: ChemComp-4UN: |
Source |
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Keywords | HYDROLASE / protein tyrosine phosphatase / WPD-loop / sulfamic acid / phosphatase / inhibitor / drug design |