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TitleStructure-based design of indole propionic acids as novel PPARalpha/gamma co-agonists
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 16, Page 4016-4020, Year 2006
Publish dateApr 28, 2006 (structure data deposition date)
AuthorsKuhn, B. / Hilpert, H. / Benz, J. / Binggeli, A. / Grether, U. / Humm, R. / Meyer, M. / Mohr, P.
External linksBioorg. Med. Chem. Lett. / PubMed:16737814
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-2gtk:
Structure-based Design of Indole Propionic Acids as Novel PPARag CO-Agonists
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-208:
(2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION REGULATOR / NUCLEAR RECEPTOR

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