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TitleThe binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal.
Journal, issue, pagesBioorg. Med. Chem., Vol. 14, Page 6055-6064, Year 2006
Publish dateMar 3, 2006 (structure data deposition date)
AuthorsLeonidas, D.D. / Maiti, T.K. / Samanta, A. / Dasgupta, S. / Pathak, T. / Zographos, S.E. / Oikonomakos, N.G.
External linksBioorg. Med. Chem. / PubMed:16730994
MethodsX-ray diffraction
Resolution1.5 - 1.7 Å
Structure data

PDB-2g8q:
The crystal structure of RNase A from monoclinic crystals at 100 K
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-2g8r:
The crystal structure of the RNase A- 3-N-piperidine-4-carboxyl-3-deoxy-ara-uridine complex
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-N3E:
1-[3-(4-CARBOXYPIPERIDIN-1-YL)-3-DEOXY-BETA-D-ARABINOFURANOSYL]PYRIMIDINE-2,4(1H,3H)-DIONE

Source
  • bos taurus (domestic cattle)
KeywordsHYDROLASE / RIBONUCLEASE / ENDONUCLEASE

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