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TitleStructure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 Bound to Mg(2+)/ATP Reveals a Non-Productive Catalytic Site.
Journal, issue, pagesJ. Mol. Biol., Vol. 359, Page 940-, Year 2006
Publish dateJan 10, 2006 (structure data deposition date)
AuthorsRamaen, O. / Leulliot, N. / Sizun, C. / Ulryck, N. / Pamlard, O. / Lallemand, J.-Y. / Van Tilbeurgh, H. / Jacquet, E.
External linksJ. Mol. Biol. / PubMed:16697012
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-2cbz:
Structure of the human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT / ABC PROTEINS / MRP1/ABCC1 / NUCLEOTIDE-BINDING DOMAIN / ATP-BINDING / HYDROLYSIS

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