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Structure paper

TitleAntithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation.
Journal, issue, pagesEmbo J., Vol. 25, Page 2029-2037, Year 2006
Publish dateMar 15, 2006 (structure data deposition date)
AuthorsJohnson, D.J. / Li, W. / Adams, T.E. / Huntington, J.A.
External linksEmbo J. / PubMed:16619025
MethodsX-ray diffraction
Resolution3.3 Å
Structure data

PDB-2gd4:
Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / serpin / Michaelis complex

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