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TitleCrystallographic studies on N-azidoacetyl-beta-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-beta-d-glucopyranosylamine.
Journal, issue, pagesBioorg. Med. Chem., Vol. 14, Page 5316-5324, Year 2006
Publish dateDec 20, 2005 (structure data deposition date)
AuthorsPetsalakis, E.I. / Chrysina, E.D. / Tiraidis, C. / Hadjiloi, T. / Leonidas, D.D. / Oikonomakos, N.G. / Aich, U. / Varghese, B. / Loganathan, D.
External linksBioorg. Med. Chem. / PubMed:16616506
MethodsX-ray diffraction
Resolution2.03 Å
Structure data

PDB-2ffr:
Crystallographic studies on N-azido-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-DL6:
N-(azidoacetyl)-beta-D-glucopyranosylamine

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsTRANSFERASE / glycogenolysis / inhibition / type 2 diabetes

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