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Structure paper

TitleThe crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment
Journal, issue, pagesStructure, Vol. 14, Page 713-723, Year 2006
Publish dateFeb 10, 2006 (structure data deposition date)
AuthorsRufer, A.C. / Thoma, R. / Benz, J. / Stihle, M. / Gsell, B. / De Roo, E. / Banner, D.W. / Mueller, F. / Chomienne, O. / Hennig, M.
External linksStructure / PubMed:16615901
MethodsX-ray diffraction
Resolution1.6 - 2.5 Å
Structure data

PDB-2deb:
Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2fw3:
Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2fyo:
Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-COA:
COENZYME A

ChemComp-PLM:
PALMITIC ACID

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-HOH:
WATER

ChemComp-BUI:
(3R)-3-{[(TETRADECYLAMINO)CARBONYL]AMINO}-4-(TRIMETHYLAMMONIO)BUTANOATE

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE / central six-stranded beta-sheet

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