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-Structure paper
Title | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity. |
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Journal, issue, pages | Protein Sci., Vol. 15, Page 710-721, Year 2006 |
Publish date | Nov 25, 2005 (structure data deposition date) |
![]() | Dunn, S.M. / Rizkallah, P.J. / Baston, E. / Mahon, T. / Cameron, B. / Moysey, R. / Gao, F. / Sami, M. / Boulter, J. / Li, Y. / Jakobsen, B.K. |
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Methods | X-ray diffraction |
Resolution | 2.1 - 2.7 Å |
Structure data | ![]() PDB-2f53: ![]() PDB-2f54: |
Chemicals | ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | IMMUNE SYSTEM / T-cell Receptor / CDR2 / Phage Display / Mutant / High Affinity / NY-ESO-1 / wild type sequence |