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TitleSpecific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 62, Page 410-416, Year 2006
Publish dateSep 15, 2005 (structure data deposition date)
AuthorsSingh, N. / Jabeen, T. / Sharma, S. / Somvanshi, R.K. / Dey, S. / Srinivasan, A. / Singh, T.P.
External linksActa Crystallogr. ,Sect. D / PubMed:16552142
MethodsX-ray diffraction
Resolution2.71 Å
Structure data

PDB-2b17:
Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: Crystal structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution:
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-DIF:
2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID / antiinflammatory, medication*YM

ChemComp-HOH:
WATER

Source
  • daboia russellii pulchella (snake)
KeywordsHYDROLASE / drugs / complex / inhibiton

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