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TitleMolecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil
Journal, issue, pagesStructure, Vol. 14, Page 589-600, Year 2006
Publish dateNov 18, 2005 (structure data deposition date)
AuthorsYamaguchi, H. / Kasa, M. / Amano, M. / Kaibuchi, K. / Hakoshima, T.
External linksStructure / PubMed:16531242
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-2f2u:
crystal structure of the Rho-kinase kinase domain
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-M77:
5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsTRANSFERASE / enzyme-inhibitor complex

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