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TitleStructural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Journal, issue, pagesMol. Cell, Vol. 21, Page 689-700, Year 2006
Publish dateApr 25, 2005 (structure data deposition date)
AuthorsPadmanabhan, B. / Tong, K.I. / Ohta, T. / Nakamura, Y. / Scharlock, M. / Ohtsuji, M. / Kang, M.-I. / Kobayashi, A. / Yokoyama, S. / Yamamoto, M.
External linksMol. Cell / PubMed:16507366
MethodsX-ray diffraction
Resolution1.6 - 1.7 Å
Structure data

PDB-1x2j:
Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1x2r:
Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSCRIPTION / beta propeller / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI

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