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Structure paper

TitleStructure of a DNA glycosylase searching for lesions.
Journal, issue, pagesScience, Vol. 311, Page 1153-1157, Year 2006
Publish dateNov 26, 2005 (structure data deposition date)
AuthorsBanerjee, A. / Santos, W.L. / Verdine, G.L.
External linksScience / PubMed:16497933
MethodsX-ray diffraction
Resolution2 - 2.35 Å
Structure data

PDB-2f5n:
MutM crosslinked to undamaged DNA sampling A:T base pair IC1
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2f5o:
MutM crosslinked to undamaged DNA sampling G:C base pair IC3
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-2f5p:
MutM crosslinked to undamaged DNA sampling A:T base pair IC2
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2f5q:
Catalytically inactive (E3Q) MutM crosslinked to oxoG:C containing DNA CC2
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-2f5s:
Catalytically inactive (E3Q) MutM crosslinked to oxoG:C containing DNA CC1
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • geobacillus stearothermophilus (bacteria)
  • synthetic construct (others)
Keywordshydrolase/DNA / disulfide crosslink / DNA glycosylase / DNA repair / damage search / hydrolase-DNA COMPLEX / control complex

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