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-Structure paper
Title | Discovery of novel hydroxy pyrazole based factor IXa inhibitor. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 2796-2799, Year 2006 |
Publish date | Jan 5, 2006 (structure data deposition date) |
Authors | Vijaykumar, D. / Sprengeler, P.A. / Shaghafi, M. / Spencer, J.R. / Katz, B.A. / Yu, C. / Rai, R. / Young, W.B. / Schultz, B. / Janc, J. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16487703 |
Methods | X-ray diffraction |
Resolution | 1.95 Å |
Structure data | PDB-2flb: |
Chemicals | ChemComp-6NH: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/BLOOD CLOTTING / active site-directed / short hydrogen bond-mediated / pyrazole-based inhibitor / HYDROLASE-BLOOD CLOTTING COMPLEX |