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TitleThe Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
Journal, issue, pagesJ. Mol. Biol., Vol. 357, Page 1202-1210, Year 2006
Publish dateOct 12, 2005 (structure data deposition date)
AuthorsDavies, D.R. / Mushtaq, A. / Interthal, H. / Champoux, J.J. / Hol, W.G.
External linksJ. Mol. Biol. / PubMed:16487540
MethodsX-ray diffraction
Resolution2.27 Å
Structure data

PDB-2b9s:
Crystal Structure of heterodimeric L. donovani topoisomerase I-vanadate-DNA complex
Method: X-RAY DIFFRACTION / Resolution: 2.27 Å

Chemicals

ChemComp-VO4:
VANADATE ION

ChemComp-HOH:
WATER

Source
  • leishmania donovani (eukaryote)
KeywordsISOMERASE/DNA / topoisomerase I / vanadate complex / ISOMERASE-DNA COMPLEX

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