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-Structure paper
Title | Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. |
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Journal, issue, pages | J. Med. Chem., Vol. 49, Page 1379-1387, Year 2006 |
Publish date | Dec 1, 2005 (structure data deposition date) |
![]() | Kovalevsky, A.Y. / Tie, Y. / Liu, F. / Boross, P.I. / Wang, Y.F. / Leshchenko, S. / Ghosh, A.K. / Harrison, R.W. / Weber, I.T. |
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Methods | X-ray diffraction |
Resolution | 1.22 - 1.45 Å |
Structure data | ![]() PDB-2f80: ![]() PDB-2f81: ![]() PDB-2f8g: |
Chemicals | ![]() ChemComp-CL: ![]() ChemComp-SO4: ![]() ChemComp-017: ![]() ChemComp-HOH: ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-ACY: |
Source |
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![]() | HYDROLASE / protein-inhibitor complex / HIV-1 protease-inhibitor complex |