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TitleStructural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs.
Journal, issue, pagesJ. Mol. Biol., Vol. 357, Page 82-99, Year 2006
Publish dateAug 1, 2005 (structure data deposition date)
AuthorsPrabakaran, P. / Gan, J. / Wu, Y.Q. / Zhang, M.Y. / Dimitrov, D.S. / Ji, X.
External linksJ. Mol. Biol. / PubMed:16426633
MethodsX-ray diffraction
Resolution2.03 Å
Structure data

PDB-2aj3:
Crystal Structure of a Cross-Reactive HIV-1 Neutralizing CD4-Binding Site Antibody Fab m18
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HIV / antibody / Fab / CD4-binding / immunoglobulin

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