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TitleStructural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 8907-8916, Year 2006
Publish dateJan 10, 2006 (structure data deposition date)
AuthorsSchoenhofen, I.C. / Lunin, V.V. / Julien, J.P. / Li, Y. / Ajamian, E. / Matte, A. / Cygler, M. / Brisson, J.R. / Aubry, A. / Logan, S.M. ...Schoenhofen, I.C. / Lunin, V.V. / Julien, J.P. / Li, Y. / Ajamian, E. / Matte, A. / Cygler, M. / Brisson, J.R. / Aubry, A. / Logan, S.M. / Bhatia, S. / Wakarchuk, W.W. / Young, N.M.
External linksJ. Biol. Chem. / PubMed:16421095
MethodsX-ray diffraction
Resolution1.5 - 3 Å
Structure data

PDB-2fn6:
Helicobacter pylori PseC, aminotransferase involved in the biosynthesis of pseudoaminic acid
Method: X-RAY DIFFRACTION / Resolution: 2.483 Å

PDB-2fni:
PseC aminotransferase involved in pseudoaminic acid biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2fnu:
PseC aminotransferase with external aldimine
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-PMP:
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE

ChemComp-UD1:
URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE

Source
  • helicobacter pylori (bacteria)
KeywordsTRANSFERASE / aminotransferase / pseudoaminic acid biosynthesis / flagellar modification / Structural Genomics / Montreal-Kingston Bacterial Structural Genomics Initiative / BSGI / protein-product complex

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