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TitleStructural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 45, Page 1267-1269, Year 2006
Publish dateJul 23, 2005 (structure data deposition date)
AuthorsCalderone, V. / Casini, A. / Mangani, S. / Messori, L. / Orioli, P.L.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:16416478
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2aeo:
Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-CU:
COPPER (II) ION

ChemComp-ZN:
Unknown entry

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsOXIDOREDUCTASE / cisplatin / platinum / SOD / cu / zn SOD / metal based drugs / cancer / protein

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