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TitleSmall-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats
Journal, issue, pagesNat. Chem. Biol., Vol. 1, Page 39-43, Year 2005
Publish dateApr 20, 2005 (structure data deposition date)
AuthorsNakatani, K. / Hagihara, S. / Goto, Y. / Kobori, A. / Hagihara, M. / Hayashi, G. / Kyo, M. / Nomura, M. / Mishima, M. / Kojima, C.
External linksNat. Chem. Biol. / PubMed:16407992
MethodsNMR (solution)
Structure data

PDB-1x26:
Solution structure of the AA-mismatch DNA complexed with naphthyridine-azaquinolone
Method: SOLUTION NMR

Chemicals

ChemComp-NAZ:
N~3~-{3-[(7-METHYL-1,8-NAPHTHYRIDIN-2-YL)AMINO]-3-OXOPROPYL}-N~1~-[(7-OXO-7,8-DIHYDRO-1,8-NAPHTHYRIDIN-2-YL)METHYL]-BET

KeywordsDNA / AA mismatch / drug

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