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-Structure paper
Title | Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays. |
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Journal, issue, pages | Biochemistry, Vol. 31, Page 6646-6659, Year 1992 |
Publish date | Apr 13, 1992 (structure data deposition date) |
![]() | Dreyer, G.B. / Lambert, D.M. / Meek, T.D. / Carr, T.J. / Tomaszek Jr., T.A. / Fernandez, A.V. / Bartus, H. / Cacciavillani, E. / Hassell, A.M. / Minnich, M. ...Dreyer, G.B. / Lambert, D.M. / Meek, T.D. / Carr, T.J. / Tomaszek Jr., T.A. / Fernandez, A.V. / Bartus, H. / Cacciavillani, E. / Hassell, A.M. / Minnich, M. / Petteway Jr., S.R. / Metcalf, B.W. |
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Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | ![]() PDB-1aaq: |
Chemicals | ![]() ChemComp-PSI: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / ACID PROTEASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX |