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Structure paper

TitleThe crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 6070-6078, Year 2006
Publish dateNov 29, 2005 (structure data deposition date)
AuthorsPayandeh, J. / Fujihashi, M. / Gillon, W. / Pai, E.F.
External linksJ. Biol. Chem. / PubMed:16377641
MethodsX-ray diffraction
Resolution1.55 - 2 Å
Structure data

PDB-2f6u:
Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with citrate
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-2f6x:
Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with sn-G1P and MPD
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

ChemComp-1GP:
SN-GLYCEROL-1-PHOSPHATE

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

Source
  • archaeoglobus fulgidus (archaea)
KeywordsTRANSFERASE / non-canonical TIM-barrel; prenyltransferase; archaeal lipid synthesis; dimer / non-canonical TIM-barrel; prenyltransferase; archaeal lipid synthesis; sn-glycerol-1-phosphate; 2-methyl-2 / 4-pentanediol; dimer

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