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-Structure paper
Title | Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 1735-1739, Year 2006 |
Publish date | Oct 20, 2005 (structure data deposition date) |
Authors | Barrett, D.G. / Catalano, J.G. / Deaton, D.N. / Hassell, A.M. / Long, S.T. / Miller, A.B. / Miller, L.R. / Ray, J.A. / Samano, V. / Shewchuk, L.M. ...Barrett, D.G. / Catalano, J.G. / Deaton, D.N. / Hassell, A.M. / Long, S.T. / Miller, A.B. / Miller, L.R. / Ray, J.A. / Samano, V. / Shewchuk, L.M. / Wells-Knecht, K.J. / Willard Jr., D.H. / Wright, L.L. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16376075 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-2bdl: |
Chemicals | ChemComp-4PR: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / cathepsin / cysteine protease / catK / catO |