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TitleStructural Analysis of Silanediols as Transition-State-Analogue Inhibitors of the Benchmark Metalloprotease Thermolysin(,).
Journal, issue, pagesBiochemistry, Vol. 44, Page 16524-16528, Year 2005
Publish dateNov 24, 2004 (structure data deposition date)
AuthorsJuers, D.H. / Kim, J. / Matthews, B.W. / Sieburth, S.M.
External linksBiochemistry / PubMed:16342943
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1y3g:
Crystal Structure of a Silanediol Protease Inhibitor Bound to Thermolysin
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-3PL:
3-PHENYLPROPANAL

ChemComp-AMM:
(2S)-2-{[(AMINOMETHYL)(DIHYDROXY)SILYL]METHYL}-4-METHYLPENTANAL

ChemComp-LEU:
LEUCINE

ChemComp-HOH:
WATER

Source
  • bacillus thermoproteolyticus (bacteria)
KeywordsHYDROLASE / silanediol protease inhibitor / thermolysin

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