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Structure paper

TitleResidues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding.
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 5258-5266, Year 2006
Publish dateNov 29, 2005 (structure data deposition date)
AuthorsMontalibet, J. / Skorey, K. / McKay, D. / Scapin, G. / Asante-Appiah, E. / Kennedy, B.P.
External linksJ. Biol. Chem. / PubMed:16332678
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2f6f:
The structure of the S295F mutant of human PTP1B
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Phosphatase / ligand binding / mutations

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