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TitleParatope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 2225-2231, Year 2006
Publish dateJul 20, 2005 (structure data deposition date)
AuthorsStaelens, S. / Hadders, M.A. / Vauterin, S. / Platteau, C. / De Maeyer, M. / Vanhoorelbeke, K. / Huizinga, E.G. / Deckmyn, H.
External linksJ. Biol. Chem. / PubMed:16314412
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-2adf:
Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ACY:
ACETIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsBLOOD CLOTTING/IMMUNE SYSTEM / on Willebrand factor / A3-domain / 82D6A3 / collagen binding / paratope / epitope / antithrombotic / BLOOD CLOTTING-IMMUNE SYSTEM COMPLEX

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