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-Structure paper
Title | Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 859-863, Year 2006 |
Publish date | Oct 17, 2005 (structure data deposition date) |
Authors | Smith III, A.B. / Charnley, A.K. / Harada, H. / Beiger, J.J. / Cantin, L.D. / Kenesky, C.S. / Hirschmann, R. / Munshi, S. / Olsen, D.B. / Stahlhut, M.W. ...Smith III, A.B. / Charnley, A.K. / Harada, H. / Beiger, J.J. / Cantin, L.D. / Kenesky, C.S. / Hirschmann, R. / Munshi, S. / Olsen, D.B. / Stahlhut, M.W. / Schleif, W.A. / Kuo, L.C. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16298527 |
Methods | X-ray diffraction |
Resolution | 1.35 - 1.7 Å |
Structure data | PDB-2bb9: PDB-2bbb: |
Chemicals | ChemComp-AKC: ChemComp-HOH: ChemComp-HH1: |
Source |
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Keywords | HYDROLASE / protease |