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-Structure paper
Title | Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors? |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 978-983, Year 2006 |
Publish date | Aug 29, 2005 (structure data deposition date) |
![]() | Adkison, K.K. / Barrett, D.G. / Deaton, D.N. / Gampe, R.T. / Hassell, A.M. / Long, S.T. / McFadyen, R.B. / Miller, A.B. / Miller, L.R. / Payne, J.A. ...Adkison, K.K. / Barrett, D.G. / Deaton, D.N. / Gampe, R.T. / Hassell, A.M. / Long, S.T. / McFadyen, R.B. / Miller, A.B. / Miller, L.R. / Payne, J.A. / Shewchuk, L.M. / Wells-Knecht, K.J. / Willard, D.H. / Wright, L.L. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.4 Å |
Structure data | ![]() PDB-2aux: ![]() PDB-2auz: |
Chemicals | ![]() ChemComp-CT1: ![]() ChemComp-HOH: ![]() ChemComp-SO4: ![]() ChemComp-CT2: |
Source |
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![]() | HYDROLASE / catK / cysteine protease |