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Structure paper

TitleCrystal Structure of the Human LRH-1 DBD-DNA Complex Reveals Ftz-F1 Domain Positioning is Required for Receptor Activity.
Journal, issue, pagesJ. Mol. Biol., Vol. 354, Page 1091-1102, Year 2005
Publish dateJul 1, 2005 (structure data deposition date)
AuthorsSolomon, I.H. / Hager, J.M. / Safi, R. / McDonnell, D.P. / Redinbo, M.R. / Ortlund, E.A.
External linksJ. Mol. Biol. / PubMed:16289203
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-2a66:
Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/DNA / nuclear receptor / protein-DNA complex / zinc finger / DNA-binding domain / transcription factor / Ftz-F1 / C-terminal extension / TRANSCRIPTION-DNA COMPLEX

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