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TitleStructural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods
Journal, issue, pagesBiochim. Biophys. Acta, Vol. 1753, Page 191-208, Year 2005
Publish dateJun 10, 2004 (structure data deposition date)
AuthorsTomoo, K. / Matsushita, Y. / Fujisaki, H. / Abiko, F. / Shen, X. / Taniguchi, T. / Miyagawa, H. / Kitamura, K. / Miura, K. / Ishida, T.
External linksBiochim. Biophys. Acta / PubMed:16271312
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1wkw:
Crystal structure of the ternary complex of eIF4E-m7GpppA-4EBP1 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GTA:
P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSLATION/PROTEIN BINDING / translation / initiation factor / cap-binding protein / mRNA-cap / TRANSLATION-PROTEIN BINDING COMPLEX

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