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Structure paper

TitleCrystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.
Journal, issue, pagesProtein Sci., Vol. 14, Page 2871-2879, Year 2005
Publish dateApr 1, 2004 (structure data deposition date)
AuthorsWu, J. / Yang, J. / Kannan, N. / Madhusudan, N. / Xuong, N.H. / Ten Eyck, L.F. / Taylor, S.S.
External linksProtein Sci. / PubMed:16253959
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1syk:
Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / E230Q mutant; Catalytic Subunit; cAMP-dependent Protein Kinase; apoenzyme conformation; N-terminal A-helix

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