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Structure paper

TitleThe structure of human SULT1A1 crystallized with estradiol. An insight into active site plasticity and substrate inhibition with multi-ring substrates
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 41482-41486, Year 2005
Publish dateJul 25, 2005 (structure data deposition date)
AuthorsGamage, N.U. / Tsvetanov, S. / Duggleby, R.G. / McManus, M.E. / Martin, J.L.
External linksJ. Biol. Chem. / PubMed:16221673
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-2d06:
Human Sult1A1 Complexed With Pap and estradiol
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-A3P:
ADENOSINE-3'-5'-DIPHOSPHATE

ChemComp-EST:
ESTRADIOL / hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SULT 1A1 / PAP / estradiol / substrarte inhibition / dead end complex

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