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TitleCrystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 40875-40884, Year 2005
Publish dateNov 24, 2004 (structure data deposition date)
AuthorsGoto, M. / Muramatsu, H. / Mihara, H. / Kurihara, T. / Esaki, N. / Omi, R. / Miyahara, I. / Hirotsu, K.
External linksJ. Biol. Chem. / PubMed:16192274
MethodsX-ray diffraction
Resolution1.55 - 1.8 Å
Structure data

PDB-1wtj:
Crystal Structure of delta1-piperideine-2-carboxylate reductase from Pseudomonas syringae pvar.tomato
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-2cwf:
Crystal Structure of delta1-piperideine-2-carboxylate reductase from Pseudomonas syringae complexed with NADPH
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-2cwh:
Crystal Structure of delta1-piperideine-2-carboxylate reductase from Pseudomonas syringae complexed with NADPH and pyrrole-2-carboxylate
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-PYC:
PYRROLE-2-CARBOXYLATE

Source
  • pseudomonas syringae pv. tomato (bacteria)
KeywordsOXIDOREDUCTASE / NADPH dependent enzyme

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