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Structure paper

TitleStructure and Reactivity of Hydroxypropylphosphonic Acid Epoxidase in Fosfomycin Biosynthesis by a Cation- and Flavin-Dependent Mechanism.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 102, Page 14221-, Year 2005
Publish dateMar 29, 2005 (structure data deposition date)
AuthorsMcluskey, K. / Cameron, S. / Hammerschmidt, F. / Hunter, W.N.
External linksProc. Natl. Acad. Sci. USA / PubMed:16186494
MethodsX-ray diffraction
Resolution1.7 - 2.5 Å
Structure data

PDB-2bnm:
The structure of Hydroxypropylphosphonic acid epoxidase from S. wedmorenis.
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2bnn:
The structure of Hydroxypropylphosphonic acid epoxidase from S. wedmorenis in complex with fosfomycin
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2bno:
The structure of Hydroxypropylphosphonic acid epoxidase from S. wedmorenis.
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-FCN:
FOSFOMYCIN / antibiotic*YM

ChemComp-HG:
Unknown entry

Source
  • streptomyces wedmorensis (bacteria)
KeywordsOXIDOREDUCTASE / EPOXIDASE / CUPIN / HTH / CATION-DEPENDANT / ZINC / FOSFOMYCIN / FOSFOMYCIN OXIDOREDUCTASE

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