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TitleKinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine
Journal, issue, pagesArch. Biochem. Biophys., Vol. 442, Page 49-58, Year 2005
Publish dateFeb 5, 2005 (structure data deposition date)
AuthorsSilva, R.G. / Pereira, J.H. / Canduri, F. / de Azevedo Jr., W.F. / Basso, L.A. / Santos, D.S.
External linksArch. Biochem. Biophys. / PubMed:16154528
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1yry:
Crystal structure of human PNP complexed with MESG
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MSG:
7-METHYL-6-THIO-GUANOSINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Purine nucleoside phosphorylase / drug design / synchrotron / MESG

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