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Structure paper

TitleAmyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.
Journal, issue, pagesNature, Vol. 437, Page 266-269, Year 2005
Publish dateAug 16, 2005 (structure data deposition date)
AuthorsSambashivan, S. / Liu, Y. / Sawaya, M.R. / Gingery, M. / Eisenberg, D.
External linksNature / PubMed:16148936
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2apq:
Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop.
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsHYDROLASE / An active site mutant of RNase A (H119A) with an amyloidogenic expansion in the C-terminal hinge-loop region(between residues 112 and 113).

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