+Search query
-Structure paper
Title | Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 48, Page 5721-5727, Year 2005 |
Publish date | Apr 18, 2005 (structure data deposition date) |
Authors | Menchise, V. / De Simone, G. / Alterio, V. / Di Fiore, A. / Pedone, C. / Scozzafava, A. / Supuran, C.T. |
External links | J. Med. Chem. / PubMed:16134940 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-1ze8: |
Chemicals | ChemComp-ZN: ChemComp-HGB: ChemComp-PIU: ChemComp-GOL: ChemComp-HOH: |
Source |
|
Keywords | LYASE / twisted beta-sheet |