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-Structure paper
| Title | The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex. |
|---|---|
| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 15, Page 4752-4756, Year 2005 |
| Publish date | Jul 22, 2005 (structure data deposition date) |
 Authors | Kohrt, J.T. / Filipski, K.J. / Cody, W.L. / Cai, C. / Dudley, D.A. / Van Huis, C.A. / Willardsen, J.A. / Rapundalo, S.T. / Saiya-Cork, K. / Leadley, R.J. ...Kohrt, J.T. / Filipski, K.J. / Cody, W.L. / Cai, C. / Dudley, D.A. / Van Huis, C.A. / Willardsen, J.A. / Rapundalo, S.T. / Saiya-Cork, K. / Leadley, R.J. / Narasimhan, L. / Zhang, E. / Whitlow, M. / Adler, M. / McLean, K. / Chou, Y.L. / McKnight, C. / Arnaiz, D.O. / Shaw, K.J. / Light, D.R. / Edmunds, J.J. |
 External links | Bioorg. Med. Chem. Lett. / PubMed:16125385 |
| Methods | X-ray diffraction |
| Resolution | 2.52 Å |
| Structure data |  PDB-2aei: |
| Chemicals |  ChemComp-CA:  ChemComp-CAC:  ChemComp-03R:  ChemComp-HOH: |
| Source |
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 Keywords | HYDROLASE / BLOOD COAGULATION / SERINE PROTEASE / THROMBOSIS / GLA / PYRIDINE / BENZAMIDINE / TISSUE FACTOR / COFACTOR / ENZYME INHIBITOR COMPLEX |
homo sapiens (human)