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TitleIdentification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
Journal, issue, pagesJ. Mol. Biol., Vol. 352, Page 597-607, Year 2005
Publish dateMay 11, 2005 (structure data deposition date)
AuthorsSaerens, D. / Pellis, M. / Loris, R. / Pardon, E. / Dumoulin, M. / Matagne, A. / Wyns, L. / Muyldermans, S. / Conrath, K.
External linksJ. Mol. Biol. / PubMed:16095608
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1zmy:
cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • camelus dromedarius (Arabian camel)
  • gallus gallus (chicken)
KeywordsIMMUNE SYSTEM/HYDROLASE / VHH; antibody; immune system; CDR grafting / IMMUNE SYSTEM-HYDROLASE COMPLEX

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