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TitleDefining Cdk5 ligand chemical space with small molecule inhibitors of Tau phosphorylation
Journal, issue, pagesChem. Biol., Vol. 12, Page 811-823, Year 2005
Publish dateJul 19, 2010 (structure data deposition date)
AuthorsAhn, J.S. / Radhakrishnan, M.L. / Mapelli, M. / Choi, S. / Tidor, B. / Cuny, G.D. / Musacchio, A. / Yeh, L. / Kosik, S.K.
External linksChem. Biol. / PubMed:16039528
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-3o0g:
Crystal Structure of Cdk5:p25 in complex with an ATP analogue
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-3O0:
{4-amino-2-[(4-chlorophenyl)amino]-1,3-thiazol-5-yl}(3-nitrophenyl)methanone

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE ACTIVATOR / kinase / Kinase activator complex / kinase inhibitor complex / TRANSFERASE-TRANSFERASE ACTIVATOR complex

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