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Structure paper

TitleThe anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 61, Page 1009-1012, Year 2005
Publish dateMar 12, 2005 (structure data deposition date)
AuthorsCanals, A. / Purciolas, M. / Aymami, J. / Coll, M.
External linksActa Crystallogr. ,Sect. D / PubMed:15983425
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-1z3f:
Structure of ellipticine in complex with a 6-bp DNA
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-EL:
ELLIPTICINE / alkaloid*YM

ChemComp-CO:
Unknown entry

ChemComp-HOH:
WATER

KeywordsDNA / ANTICANCER / DNA BINDING / DRUG DESIGN / ELLIPTICINE / INTERCALATOR

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