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Structure paper

TitleStructure of human PNP complexed with ligands.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 61, Page 856-862, Year 2005
Publish dateNov 9, 2003 (structure data deposition date)
AuthorsCanduri, F. / Silva, R.G. / dos Santos, D.M. / Palma, M.S. / Basso, L.A. / Santos, D.S. / de Azevedo, W.F.
External linksActa Crystallogr. ,Sect. D / PubMed:15983407
MethodsX-ray diffraction
Resolution2.85 - 2.9 Å
Structure data

PDB-1rfg:
Crystal Structure of Human Purine Nucleoside Phosphorylase Complexed with Guanosine
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-1v41:
Crystal structure of human PNP complexed with 8-Azaguanine
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-1v45:
Crystal Structure of human PNP complexed with 3-deoxyguanosine
Method: X-RAY DIFFRACTION / Resolution: 2.86 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GMP:
GUANOSINE

ChemComp-HOH:
WATER

ChemComp-AZG:
5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL / antineoplastic*YM

ChemComp-3DG:
9-(3-DEOXY-BETA-D-RIBOFURANOSYL)GUANINE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PURINE NUCLEOSIDE PHOSPHORYLASE / DRUG DESIGN / SYNCHROTRON / GUANOSINE / sybcgritron / 8-azaguanine

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