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TitleStructural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.
Journal, issue, pagesBiochemistry, Vol. 44, Page 8634-8642, Year 2005
Publish dateOct 29, 2004 (structure data deposition date)
AuthorsJonsson, T.J. / Murray, M.S. / Johnson, L.C. / Poole, L.B. / Lowther, W.T.
External linksBiochemistry / PubMed:15952770
MethodsX-ray diffraction
Resolution1.65 - 2 Å
Structure data

PDB-1xw3:
Crystal Structure of Human Sulfiredoxin (Srx)
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-1xw4:
Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / retroreduction / sulfinic acid / peroxiredoxin / ATP / sulfiredoxin / cysteine / sulphiredoxin

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