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TitleThe Crystal Structure of a c-Src Complex in an Active Conformation Suggests Possible Steps in c-Src Activation
Journal, issue, pagesStructure, Vol. 13, Page 861-871, Year 2005
Publish dateDec 2, 2004 (structure data deposition date)
AuthorsCowan-Jacob, S.W. / Fendrich, G. / Manley, P.W. / Jahnke, W. / Fabbro, D. / Liebetanz, J. / Meyer, T.
External linksStructure / PubMed:15939018
MethodsX-ray diffraction
Resolution1.91 Å
Structure data

PDB-1y57:
Structure of unphosphorylated c-Src in complex with an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MPZ:
4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-N-{3-[(4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO]PHENYL}BENZAMIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase structure / SH3 / SH2

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