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Structure paper

TitleAnthrax lethal factor inhibition.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 102, Page 7958-7963, Year 2005
Publish dateFeb 2, 2005 (structure data deposition date)
AuthorsShoop, W.L. / Xiong, Y. / Wiltsie, J. / Woods, A. / Guo, J. / Pivnichny, J.V. / Felcetto, T. / Michael, B.F. / Bansal, A. / Cummings, R.T. ...Shoop, W.L. / Xiong, Y. / Wiltsie, J. / Woods, A. / Guo, J. / Pivnichny, J.V. / Felcetto, T. / Michael, B.F. / Bansal, A. / Cummings, R.T. / Cunningham, B.R. / Friedlander, A.M. / Douglas, C.M. / Patel, S.B. / Wisniewski, D. / Scapin, G. / Salowe, S.P. / Zaller, D.M. / Chapman, K.T. / Scolnick, E.M. / Schmatz, D.M. / Bartizal, K. / MacCoss, M. / Hermes, J.D.
External linksProc. Natl. Acad. Sci. Usa / PubMed:15911756
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1yqy:
Structure of B. Anthrax Lethal factor in complex with a hydroxamate inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-915:
(2R)-2-{[(4-FLUORO-3-METHYLPHENYL)SULFONYL]AMINO}-N-HYDROXY-2-TETRAHYDRO-2H-PYRAN-4-YLACETAMIDE

ChemComp-HOH:
WATER

Source
  • bacillus anthracis (anthrax bacterium)
KeywordsHYDROLASE / Toxin / Lethal Factor / inhibitors / hydroxamate

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